Which route involves absorption through the mucous membranes in the mouth?

Which route involves absorption through the mucous membranes in the mouth?

• A. Inhalation
• B. Rectal administration
• C. Buccal administration
• D. Snorting

Answer: (C)

Absorption through mouth mucous membranes is the buccal route. The inner cheek mucosa has a rich blood supply and a thin surface, allowing a drug placed there to pass quickly into the bloodstream. This route can produce a fast onset and bypass some liver metabolism compared with swallowing a pill, since the drug enters systemic circulation more directly. Inhalation uses the lungs, rectal administration uses the rectal lining, and snorting uses the nasal mucosa. So, the method that involves absorption through the mouth’s mucous membranes is buccal administration.

Absorption through mouth mucous membranes is the buccal route. The inner cheek mucosa has a rich blood supply and a thin surface, allowing a drug placed there to pass quickly into the bloodstream. This route can produce a fast onset and bypass some liver metabolism compared with swallowing a pill, since the drug enters systemic circulation more directly. Inhalation uses the lungs, rectal administration uses the rectal lining, and snorting uses the nasal mucosa. So, the method that involves absorption through the mouth’s mucous membranes is buccal administration.